Research
Metabolic Function
Overview
iWorx Metabolic Measurement Solutions are compact, cost effective and easy-to-use systems capable of accurately and reliably measuring and analyzing oxygen consumption and carbon dioxide production in resting and exercising subjects in support of:
– Human exercise physiology research
– Small animal metabolic research
– Fitness assessment
Human Applications
MC-PEAK Metabolic Cart for Human VO2 Max Measurement
Compact Integrated metabolic system for measuring Basal Metabolic Rate, Resting Metabolic Rate, Respiratory Exchange Ratio, Sedentary to light activity VO2 and VCO2, and VO2 Max.
MC-TA-200V Metabolic Cart for Human VO2 Max Measurement
The MC-TA-200V is optimized for recording and measuring Basal Metabolic Rate, Resting Metabolic Rate, Respiratory Exchange Ratio, Sedentary to light activity VO2 and VCO2, and VO2 Max. The system includes the GA-200 Gas Analyzer,TA control module, spirometer, Polar Heart Rate Monitor/Transmitter/Receiver, mixing chamber and LabScribe software with the Metabolic Calculations Module.
Animal Applications
MC-520Peak and MC-140Peak Small Animal Metabolic Carts
These systems are suitable for recording and measuring Respiratory Quotient, VO2 and VCO2 in small- to medium-size animals. The systems include the IX-Peak recorder and Gas Analyzer, LabScribe software with the Metabolic Calculations Module and either a 1.4 L or 5.2 L animal chamber.
SAMC4 MultiChamber Small Animal Metabolic Carts
MultiChannel small animal metabolic systems are suitable for recording and measuring Respiratory Quotient, VO2 and VCO2 in small- to medium-size animals. The systems include the IX-TA-220 recorder , iWire-GA1 Gas Analyzer, A-GS-8 Gas Switcher, LabScribe software with the Metabolic Calculations Module and 4 animal chambers( 1.4 L or 5.2 L) .

LabScribe Metabolic Calculations
LabScribe automates and streamlines both the analysis and reporting of metabolic parameters from a test subject. The calculations are derived from the input data acquired during a test which would typically include oxygen and carbon dioxide concentrations, lung volumes, and heart rates. Raw data can be viewed in real-time within the LabScribe Main window.Setup and Calibrate:
Streamlined setup and calibration reduces error and saves time.Measure:
- Relative and absolute oxygen consumption (VO2)
- Relative and absolute carbon dioxide production (VCO2)
- Respiratory Exchange Ratio (RER)
- Ventilatory Equivalent (VE/VO2)
- Expired Minute Ventilation (VE)
- Metabolic Equivalent (METS) and more
Plot:
The Metabolic Calculations Module also allows these parameters to be plotted against time or each other to yield valuable information about the aerobic fitness of the subject. These plots include:- VO2, VCO2, RER vs. Time
- VCO2 vs. VO2
- VE vs. VO2
- VE vs. VCO2
- HR, VCO2 vs. VO2
- %Fat
- VE vs. Watts
- HR, VO2/HR vs. Watts
- VO2, VCO2 vs. Watts
- VE/VO2, VE/VCO2 Vs. Watts
- Resting Energy Expenditure (REE)
- It is now possible to setup and save a subject profile while performing a fitness assessment test. During subsequent tests, the same subject profile can be loaded and data can be easily compared. This feature provides a convenient and simple way to track progress over time.
- An intuitive user interface has been created to setup and customize training zones for subjects based on % of maximum heart rate or within a specific heart rate range.
Control Exercise Equipment
- Treadmills: Treadmill that support the Trackmaster Protocol, such as treadmills from Trackmaster, Woodway can be controlled by Labscribe
- Ergometers : Ergometers supporting the ANT+ FEC Trainer protocol can be controlled by LabScribe
- Lode Ergometer: Lode Ergometers can be controlled by LabScribe.
Record ANT+ Sensor Data
Record data from various ANT+ sensors such as.- Heart Rate Sensors
- Bike Power Sensors
- Muscle Oxygen Sensors
- MSSU 01 - Initial Flowhead Calibration
- MCSU 2 - Metabolic Cart Setup for different systems.
HEK-PEAK IX-TA & iWire-GA | IX-TA & GA-200 | IX-TA & GA-300 | IX-214 & GA-200 | IX-214 & GA-300 |
- MCSU 3 -iWorx Metabolic Cart Setup - Flowhead Calibration
- MCSU 4 - iWorx Metabolic Cart Setup - O2/CO2 Calibration
- MCGS 01 - Subject Setup
- MCGS 02 - Quick Flow Calibration
- MCGS 03 - Calibrate Gas Analyzer
- MCGS 04 - Protocol Selection
- MCGS 05 - VO2 Max Test
- MCGS 06 - Data Analysis
- Keene State College Teaching and Learning Commons: VO2 Max test
- MC1 - Rowing VO2max Test
Using GA-200 Gas Analyzer
- Pillay, Kineshta, et al. "Inhaled Nitric Oxide: In Vitro Analysis of Continuous Flow Noninvasive Delivery via Nasal Cannula." Respiratory Care (2020).
- Tas, Basak, et al. "Heroin‐induced respiratory depression and the influence of dose variation: within‐subject between‐session changes following dose reduction." Addiction (2020).
- Moore, C. P., et al. "High flow nasal cannula: Influence of gas type and flow rate on airway pressure and CO2 clearance in adult nasal airway replicas." Clinical Biomechanics 65 (2019): 73-80.
- Moore, Charles P., et al. "Correlation of high flow nasal cannula outlet area with gas clearance and pressure in adult upper airway replicas." Clinical Biomechanics (2017).
- Merritt, Kristen J., Caroline E. Raburn, and Jesse C. Dean. "Adaptation of the preferred human bouncing pattern toward the metabolically optimal frequency." Journal of neurophysiology 107.8 (2012): 2244-2249.
- Bowtell, Joanna L., et al. "Acute physiological and performance responses to repeated sprints in varying degrees of hypoxia." Journal of Science and Medicine in Sport 17.4 (2014): 399-403.
- Gómez, Jaime Vásquez, et al. "DESEMPEÑO EN UNA PRUEBA DE CAMINATA Y UNA PRUEBA INCREMENTAL EN ESTUDIANTES DE EDUCACIÓN FÍSICA: FRECUENCIA CARDÍACA DE RECUPERACIÓN Y VO2 MÁX." Revista Ciencias de la Actividad Física UCM. N 16.2 (2015): 57-69.
- Gravelle, Brent L., and Ted W. Hagen II. "Metabolic characteristics of Appalachian children." Clinical Nutrition ESPEN (2017).
- Dutta, Rabijit, et al. "Comparison of flow and gas washout characteristics between pressure control and high-frequency percussive ventilation using a test lung." Physiological measurement 39.3 (2018): 035001.
- Dutta, Rabijit, Tao Xing, and Gordon K. Murdoch. "Comparison of pressure, volume and gas washout characteristics between PCV and HFPV in healthy and formalin fixed ex vivo porcine lungs." Physiological measurement 39.9 (2018): 095003.
- Kumar, Sunil, et al. “Estimation of metabolic heat production and methane emission in Sahiwal and Karan Fries heifers under different feeding regimes.” Veterinary world 9.5 (2016): 496.
- Wooding, Denise J., et al. “Increased Protein Requirements in Female Athletes after Variable-Intensity Exercise.” Medicine & Science in Sports & Exercise (2017).
- Garner, Sarah N., and Linda G. Jones. “THE ROLE OF BODY HABITUS ON AEROBIC FITNESS IN NCAA BASKETBALL PLAYERS.” Georgia Journal of Science 75.1 (2017): 55.